Martha A. Hass, PhD
Education
- PhD, Organic Chemistry, Rensselaer Polytechnic Institute
Courses at Taught at ACPHS
- Downstream Processing of Biopharmaceutical Products
- Technical Writing for the Biopharmaceutical Industry
- Scientific Communication
- Organic Chemistry I & II
- Seminar I & II
- Pharmaceutical Analytical Techniques I
Research Interests
- Our lab works on the synthesis of novel co-drugs aimed at treating skin diseases, the development of stable topical formulations for these compounds, assessment of penetration and accumulation of topical experimental drugs in skin (using an ex vivo skin model) and evaluating efficacy using in vitro assays.
Research Grants
- Dr. Hass was awarded a three year research grant in 2011 from the National Institutes of Health to develop a series of chemical compounds that could prove instrumental in limiting the harmful effects of the sun’s ultraviolet (UV) rays.
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Publications
- Levin RM, Schuler C, Leggett RE, Hass MA. The effect of α- and δ-tocopherol-lipoic acid ester co-drugs on the response of the rabbit bladder to in-vitro ischemia/reperfusion. Turkish Journal of Urology 2018 DOI: 10.5152/tud.2018.48154.
- Thomas, S.; Vieira, C.S.; Lopes, L.B.; Hass, M.A. Stability, cutaneous delivery and antioxidant potential of a lipoic acid and tocopherol co-drug incorporated in nanodipersed systems. J Pharm Sci. 2014 103 (8):2530-8.
- Cichewicz, A.; Pacleb, C; Connors, A.; Hass, M.A.; Lopes, L.B. Cutaneous co-localization of α-tocopherol and lipoic acid using microemulsions: influence of composition and charge. J.Pharm and Pharmacol. 26 FEB 2013. DOI: 10.1111/jphp.12045.
- Yao, X; Dai, Y.; Johnson, A.; Feleder, C.; Hass, M.A. Determination of Prostaglandin Profiles in LPS-Challenged Guinea Pig Spleen, Biomed. Chromatography, 27(3):284-91, 2013.
- Pepe, D.; Phelps, J.; Lewis, K.; DuJack, J.; Scarlett, K.; Jahan, S.; Bonnier,E.;Milic-Pasetto,T.; Hass, M.A.; Lopes, L. B. Decylglucoside-based microemulsions for cutaneous localization of lycopene and ascorbic acid., Int. J. Pharm. 434 420– 428, 2012.
- Lopes, L.B.; Vanderwall, H.; Li, H.T.; Venugopal, V.; Li, H.K.; Naydin, S.; Hosmer, J.; Bentley, M.V.L.B.; Levendusky, M.; Hass, M.A.; Levin, R.; Zheng, H. Enhancement of Topical Devlivery of Lycopene Using Microemulsions. J. Pharm Sci. 99(3) 1346-57, 2010.
- Hass, MA and Moon, D. “Natural Products” in Pharmacy Practice for Technicians, 3rd edition. Hanan, Z. I. and Dugan, J.M, eds., Thomson Delmar Learning: Clifton Park, NY, 2004.
- Hass, M..A. and Levin, R.M. “The Role of Lipids and Lipid Metabolites in Urinary Bladder Dysfunction Induced by Partial Outlet Obstruction” in Bladder Disease: Research Concepts and Applications, Atala, A. and Slade, D., eds., Kluwer Academic Publishers, 2004.
- Hass, MA; Levin RM. The Role of Lipids and Lipid Metabolites in Urinary Bladder Dysfunction Induced by Partial Outlet Obstruction. Adv. Exp. Med. Biol. 2003; 539 (Pt A0:217-37).
- Levin, RM; Chichester, P; Hass, MA; Gosling, JA; Buttyan, R. Obstructive Bladder Dysfunction: Morphological, Biochemical and Molecular Changes. Eur. Urol. Suppl 2002, 14-20.
Conferences and Presentations
Vadgama R, Hass MA. Prodrug Therapy for the Treatment of Psoriasis: Formulation, Stability and Drug Delivery to the Skin. 18th Annual AAPS Northeast Regional Discussion Group, Farmington CT, April 12, 2018.